How Long Does Morphine Stay In System?

Doctor prescribes morphine.

Morphine is usually prescribed when you’re experiencing severe pain that can not be relieved by other painkillers or chronic pain that has lasted more than a couple of days. Because it is an opioid, it is rather effective and can also be prescribed for other types of pain like pain caused by a heart attack, cancer, an injury, or major surgery. Whatever be the reason, if you have been prescribed morphine, you might find yourself asking questions like how long does morphine stay in your system? This is a valid question. Equally important is finding out ways to avoid experiencing withdrawal symptoms when you stop taking the drug.

How Does Morphine Work?

Morphine is effective because it works by preventing pain signals from getting to the brain. Because it works in the pleasure centers of the brain, its potential for misuse and abuse is high. This is why it is classified as a Schedule II controlled substance.

Morphine Brand Names

The following are morphine brand names:

  • Roxanol
  • MXL
  • Morphgesic
  • Kadian
  • Sevredol
  • Oramorph SR
  • MorphaBond ER
  • MS Contin
  • Zomorph
  • Arymo ER

Morphine Half-Life

The half-life of a drug is a parameter used to determine the amount of time it takes for the total quantity in the body to be reduced by 50%. It is also one of the ways to figure out how long a drug will last in the body. In this case, one half-life will refer to the time the concentration of the morphine dosage will become half of the initial starting dose. Morphine IR (Immediate Release) and morphine pill are two ways to introduce morphine into the body system.

Although the half-life of morphine differs from one person to another due to individual differences in medication metabolism, the average half-life of morphine is between two to four hours.

How Long Does Morphine Last?

If morphine dosage for adults is taken orally, the pain-relieving effect of morphine becomes noticeable within 30 to 60 minutes, and it will reach its peak concentration in the bloodstream within 60 minutes. If injected, however, its effect is felt sooner. The effects of extended-release formations like the morphine sulfate er take longer and last between eight to twelve hours.

The pain-relieving effect of morphine might last for four to six hours, after which you’d stop feeling its effects. This is why your dosage might be a particular measurement of liquid morphine or a single tablet every four to six hours.

The effect of morphine will wear off after a while, but morphine will last in your system for a longer period. A drug is fully eliminated from the body only after several half-lives. So although the average morphine half-life is two to four hours, it can last in the blood for as long as 12 hours after the last dose is taken. But even when it is completely cleared from the blood, it can still be detected in the urine, hair, and saliva for a while.

Morphine er, morphine liquid, morphine tablets, and morphine injection are some of the different ways in which morphine can be prescribed. The dosage is important to ensure that it doesn’t reach an overdose level in the body.

Factors that Influence on Morphine Staying in System

As earlier stated, morphine clears faster in the body of some people for different reasons. These factors include:

  • Dosage
  • Presence of other medications in the blood
  • Metabolism
  • Age
  • Pre-existing medical conditions
  • Presence of alcohol in the body system
  • Weight and mass of the body
  • If you have taken any opioid in the past
  • Body fat
  • Kidney and liver function
  • Length of time you have been taking morphine

How Long Does Morphine Stay in Urine, Blood, and Saliva?

Although morphine cannot be detected in the blood after 12 hours, the same cannot be said for detecting it in the urine and saliva.

  • How long does morphine stay in your urine? The American Addiction Centers states that the presence of morphine can be detected for as long as 3 days in the urine.
  • How long can morphine stay in the saliva? Morphine can stay in the saliva for as long as 4 days.
  • Lastly, morphine can be detected in the hair for 90 days from the time the last dose is ingested.